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SIBO Breath Test Cost: Compare 9 Prices
How much does the SIBO hydrogen/methane breath test (3-hour lactulose) cost? We found 9 posted prices from 9 sellers, from $235 to $359 including separately listed fees. The cheapest SIBO breath test price open to the public was $249 at Direct Laboratory Services (DirectLabs). The lowest overall ($235) is limited to that clinic's own patients. Last checked Oct 19, 2026.
What it measures
Hydrogen and methane in exhaled breath, collected at intervals after drinking a lactulose solution, to look for bacterial overgrowth in the small intestine (per lab and seller descriptions).
Lab: Mostly Genova Diagnostics (lab varies by seller) · Specimen: Breath samples collected at home over 3 hours after a lactulose drink
Evidence level: Widely used, with known limits
A North American expert consensus (Rezaie et al., Am J Gastroenterol, 2017) describes glucose and lactulose breath tests as the least invasive alternatives to diagnose SIBO, while noting that standardization of indications, methodology and interpretation had been lacking; it proposed standard doses and cut-offs (e.g. a hydrogen rise of ≥20 ppm by 90 minutes; methane ≥10 ppm).
Sources:
- Rezaie A, et al. Hydrogen and Methane-Based Breath Testing in Gastrointestinal Disorders: The North American Consensus. Am J Gastroenterol. 2017;112(5):775-784.. https://pmc.ncbi.nlm.nih.gov/articles/PMC5418558/
Tiers: Established · Widely used, with known limits · Emerging · Not validated · Not yet reviewed. We publish a tier only when we can cite a guideline, systematic review or major professional-society statement. This summary describes published literature and is not a recommendation to take or skip any test.
SIBO Breath Test prices, lowest total first
| Seller | Price | Listed fees | Total | Who can order | Notes | Links |
|---|---|---|---|---|---|---|
| My Path Functional MedicineLOWEST | $225 | $10 kit ordering/handling | $235 | Clinic patients only | Genova. | ViewReport a wrong price |
| Direct Laboratory Services (DirectLabs) | $249 | $0 listed | $249 | Self-order | Genova 3-hr lactulose. | ViewReport a wrong price |
| Genova Connect (Genova Diagnostics, direct) | $250 | $15 physician fee | $265 | Self-order | 3-hour lactulose. Not available in NY, NJ, RI. | ViewReport a wrong price |
| DHA Laboratory | $282 | $0 listed | $282 | Self-order (physician-partner program) | 3-hr. | ViewReport a wrong price |
| Walk-In Lab | $299 | $6 physician fee | $305 | Self-order | Genova 3-hr. | ViewReport a wrong price |
| True Health Labs | $329 | $0 listed | $329 | Self-order | Genova 3-hr lactulose. Site blocks automated fetch; price read via web search page extract. (price read manually; site blocks automated checks) | ViewReport a wrong price |
| NuGene Labs | $348 | $0 listed | $348 | Self-order | Genova 3-hr. | ViewReport a wrong price |
| Labs by Request | $350 | $0 listed | $350 | Self-order | ViewReport a wrong price | |
| Instalab | $359 | $0 listed | $359 | Self-order | Instalab+ members price shown as $269. | ViewReport a wrong price |
Totals add only fees each seller lists on its product page (e.g., physician-authorization fees). Shipping, blood-draw, sales tax and state availability may vary. Links may become affiliate links in future; see our disclosure.
SIBO Breath Test FAQ
How much does a SIBO breath test cost?
On Oct 19, 2026, 9 posted prices from 9 sellers ranged from $235 to $359 including listed fees (median $305). The lowest price open to the public was $249 at Direct Laboratory Services (DirectLabs). The lowest overall, $235 at My Path Functional Medicine, is limited to that clinic's own patients. The lab's own store, Genova Connect (Genova Diagnostics, direct), listed $265.
Are all SIBO tests the same?
No. Substrate (lactulose vs glucose), duration (2 vs 3 hours) and gases measured differ. This page compares 3-hour lactulose tests; rows note the lab.
Is there preparation?
Yes. Sellers describe a restricted diet the day before and fasting; follow the kit instructions.
What's included in the SIBO breath test price?
Each row is the seller's listing for the SIBO hydrogen/methane breath test (3-hour lactulose) (lab: Mostly Genova Diagnostics (lab varies by seller); specimen: Breath samples collected at home over 3 hours after a lactulose drink). The Total column adds fees the seller lists on the product page: Genova Connect (Genova Diagnostics, direct) ($15 physician fee), My Path Functional Medicine ($10 kit ordering/handling), Walk-In Lab ($6 physician fee). Shipping, tax, blood draws and consultations are not included unless the row says so.
Do you need a doctor's order for a SIBO breath test?
Usually not. 8 of 9 listings here are marked self-order: you can buy without bringing your own doctor's order. Some add a listed physician or handling fee, included in the Total. 1 is sold only to a clinic's existing patients. Check the 'Who can order' column.
Which states restrict ordering a SIBO breath test?
Sellers in our table note these limits: Genova Connect (Genova Diagnostics, direct): Not available in NY, NJ, RI. State rules for consumer-ordered lab tests vary and sellers may block some states at checkout, so confirm on the seller's page.
Why do prices differ so much?
Sellers set their own prices for the same lab's kit and may bundle practitioner authorization, consultations, shipping or add-ons. The table shows the price and any separately listed fees as posted on each seller's public page on the date checked.
How current are these prices?
All prices were checked on Oct 19, 2026. Prices and availability (including state restrictions) change; confirm on the seller's page before ordering.
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