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H. pylori breath test vs stool test: how they differ and what they cost

The urea breath test and the stool antigen test both look for a current Helicobacter pylori infection; a blood antibody test is a different test. Here is how each works, what the guideline says about them, and what each costs at the sellers we track (checked Oct 20, 2026).

Urea breath testStool antigen test
How it works (MedlinePlus)You drink or swallow labeled urea; "if you have H. pylori, the bacteria will change the urea into carbon dioxide", which shows up in a breath sampleThe lab "checks your sample for antigens that come from H. pylori"
Listings we track$83.52–$259 (7 listings)$74–$299 (4 listings)
Lowest open to the public$110.93 at Mito Health (non-member price)$74 at Walk-In Lab

What the guideline says

The 2024 American College of Gastroenterology guideline on treating H. pylori states that everyone treated should have a test of cure using a urea breath test, a fecal (stool) antigen test or a biopsy-based test at least 4 weeks after finishing therapy, and describes breath and fecal antigen tests as highly accurate for confirming treatment success. Proton pump inhibitors and recent antibiotics can cause false-negative results. MedlinePlus notes that "you may need to stop taking certain medicines for two weeks to a month" before testing; ask the ordering clinician which ones.

Blood antibody tests are different: MedlinePlus explains that the test "can't show whether the antibodies are from an active H. pylori infection that you have now" or a past one. The listings below are breath and stool tests only. Our evidence level for breath and stool testing: Established. This page is not advice on which test to use; that is a question for a clinician.

Every listing we track, lowest total first

Seller and listingTypeTotalWho can order
Walk-In Lab
H. pylori Antigen Stool Test
Stool antigen$74Self-order
Mito Health (member price)
H. pylori Urea Breath Test
Breath$83.52Members only ($9/mo or $99/yr membership)
Mito Health (non-member price)
H. pylori Urea Breath Test
Breath$110.93Self-order
TestWell
H. pylori Breath Test
Breath$135.99Self-order
TestWell
H. pylori Stool Antigen
Stool antigen$155.99Self-order
Walk-In Lab
H. pylori Urea Breath Test
Breath$205Self-order
Labcorp OnDemand
H. pylori Urea Breath Test
Breath$209Self-order
True Health Labs
H. pylori Breath Test
Breath$229Self-order
Direct Laboratory Services (DirectLabs)
H. pylori Urea Breath Test
Breath$259Self-order
Direct Laboratory Services (DirectLabs)
H. pylori Antigen EIA, stool
Stool antigen$279Self-order
True Health Labs
H. pylori Stool Antigen (Quest)
Stool antigen$299Self-order

Totals include fees each seller lists on its product page. State limits and notes are on the H. pylori price table.

Compare prices

Sources

  1. Chey WD, et al. ACG Clinical Guideline: Treatment of Helicobacter pylori Infection. Am J Gastroenterol. 2024;119(9):1730-1753. https://www.ovid.com/jnls/ajg/fulltext/10.14309/ajg.0000000000002968~acg-clinical-guideline-treatment-of-helicobacter-pylori
  2. MedlinePlus: Helicobacter Pylori (H. pylori) Tests https://medlineplus.gov/lab-tests/helicobacter-pylori-h-pylori-tests/

Sources checked 2026-10-19. Prices are from our price tables and update when we re-check sellers.

Informational only, not medical advice. See about & disclaimer.

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